The Biggert Collection contains vignettes from across the United States, representing approximately 350 locations.
| City | State | Number of Items |
|---|---|---|
| Devils Lake, Dakota | North Dakota | 1 |
| Dillon | Montana | 1 |
| Dover | New Hampshire | 2 |
| Dubuque | Iowa | 6 |
| Duluth | Minnesota | 2 |
| Durhamville | New York | 1 |
| Eagles Mere | Pennsylvania | 1 |
| East Haddam | Connecticut | 1 |
| East Syracuse | New York | 1 |
| Easton | Pennsylvania | 0 |
| Eau Claire | Wisconsin | 0 |
| Elizabeth | New Jersey | 1 |
| Elizabethtown | Kentucky | 1 |
| Elkhart | Indiana | 2 |
| Elkland | Pennsylvania | 1 |
| Elmira | New York | 2 |
| Endicott | New York | 1 |
| Erie | Pennsylvania | 5 |
| Euclid Beach Park | Ohio | 1 |
| Evansville | Indiana | 1 |